Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins
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چکیده
منابع مشابه
Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins.
A large superfamily (> 50 members) of monomeric GTPbinding proteins structurally related to the ras oncogene proteins has been described in the past few years (Bourne et al., 1991; Grand and Owen, 1991; Hall, 1990; Valencia et al., 1991). These proteins have been implicated in the regulation of a diverse array of cellular processes, utilizing their ability to bind and hydrolyse GTP as a means t...
متن کاملEmerging concepts in the Ras superfamily of GTP-binding proteins.
The Ras superfamily of GTP-binding proteins (> 50 members) regulates a diverse spectrum of intracellular processes. These include cellular proliferation and differentiation, intracellular vesicular trafficking, cytoskeletal control, NADPH oxidase function, as well as others. In this review, we describe recent progress and emerging themes in the action and regulation of these important cellular ...
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Over the past several years, a large superfamily of monomeric GTP-binding proteins structurally related to the ras oncogene proteins has been described (1-4). The number of members of this superfamily identified has increased dramatically in recent years, and the number of descriptive terms or names used to denote these proteins has increased almost as dramatically as well. During the recent FA...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1993
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2890017